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Triclosan°ú Pyrophosphate ¹× Tranexamic acid¸¦ ¹èÇÕÇÑ ¼¼Ä¡Á¦ÀÇ Ä¡ÁÖÁúȯ¿øÀαհú ±¸ÃëÀ¯¹ß¿øÀαտ¡ ´ëÇÑÇ×±ÕÈ¿°ú¿¡ °üÇÑ ¿¬±¸

The effect of dentifrice containing triclosan, pyrophosphate and tranexamic acid on the antimicrobial activity against the pathogens of periodontal disease and halitosis.

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Abstract

°á·Ð
ÀúÀÚµéÀº Ä¡ÁÖº´ ¿¹¹æ¹°Áú·Î ¾Ë·ÁÁø triclosan°ú tranexamic acid ¹× pyrophosphate¸¦ °ø
È÷ ¹èÇÕÇÑ ¼¼Ä¡Á¦ÀÇ Ä¡ÁÖÁúȯ¿øÀαհú ±¸ÃëÀ¯¹ß¿øÀαտ¡ ´ëÇÑ Ç×±ÕÈ¿°ú¸¦ È®ÀÎÇÒ ¸ñÀûÀ¸·Î,
Èñ¼®¹ý°ú ¿øÆÇÈ®»ê¹ýÀ» ¼öÇàÇÏ¿© Streptococcus sanguis 10556, Actinomyces viscosus
15987, Candida albicans 10231, Actinobacillus actinomycetemcomitans (Y4),
Capnocytophaga ochracea 27872, Fusobacterium nucleatum 25586, Prevotela intermedius
9336, Phopyromonas gingivalis 381¿¡ ´ëÇÑ ½ÇÇ輼ġÁ¦¿Í ´ëÁ¶¼¼Ä¡Á¦ÀÇ ¼¼±Õ¹ßÀ°¾ïÁ¦Á¤µµ¸¦
ÃøÁ¤ ºñ±³ °ËÅäÇÑ °á°ú, ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
1. Triclosan°ú tranexamic acid ¹× pyrophosphate¸¦ °øÈ÷ ¹èÇÕÇÑ ½ÇÇ輼ġÁ¦´Â ÀÌµé ¼ººÐ
µéÀÌ ¹èÇյǾî ÀÖÁö ¾ÊÀº ´ëÁ¶¼¼Ä¡Á¦¿¡ ºñÇÏ¿© Ä¡ÁÖÁúȯ¿øÀαհú ±¸ÃëÀ¯¹ß¿øÀαÕÀ¸·Î ¾Ë·Á
Áø Actinobacillus actinomycetemcomitans (Y4), Capnocytophaga ochracea 27872,
Phopyromonas gingivalis 381¿¡¼­ º¸´Ù °­ÇÑ Ç×±ÕÈ¿°ú¸¦ ³ªÅ¸³»¾ú´Ù.
2. Triclosan°ú tranexamic acid ¹× pyrophosphate¸¦ °øÈ÷ ¹èÇÕÇÑ ½ÇÇ輼ġÁ¦¿Í ÀÌµé ¼ººÐ
µéÀÌ ¹èÇյǾî ÀÖÁö ¾ÊÀº ´ëÁ¶¼¼Ä¡Á¦´Â °øÈ÷ Streptococcus sanguis 10556, Actinomyces
viscocus 15987, Candida albicans 10231, Actinobacillus actinomycetemcomitans (Y4),
Capnocytophaga ochracea 27872, Fusobacterium nucleatum 25586 Prevotela intermedius
9336, Phopyromonas gingivalis 381¿¡ ´ëÇÑ Ç×±ÕÈ¿°ú°¡ ÀÖ¾ú´Ù.

The antimicrobial effects of dentifrice containing triclosan, pyrophosphate and
tranexamic acid against the pathogens of periodontal disease and halitosis such as
Streptococcus sanguis, Actinomyces viscosus, Candida albicans, Actinobacillus
actinomycetemcomitans, Capnocytophaga ochracea, Fusobacterium nucleatum, Prevotela
intermedius, Phopyromonas gingivalis were evaluated with the agar dilution and paper
disc methods.
The results obtained were as follows:
1. Both the experimental dentifrice containing triclosan, pyrophosphate and tranexamic
acid and the control dentifrice showed the antimicrobial activities on all the
microorganisms tested.
2. The experimental dentifrice containing triclosan, pyrophosphate and tranexamic acid
showed more effective antimicrobial activities on Actinobacillus actinomycetemcomitans,
Capnocytophaga ochrcea, Phopyromonas gingivalis, relative to the control dentifrice.

Å°¿öµå

triclosan; pyrophosphate; tranexamic acid;

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